Bleeding Lungs and Tamiflu-resistance -Do H1N1 mutations make the swine flu vaccine less effective?

from : ukraineplague.blogspot.com/

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H1N1 mutations are being found all over the world, including in the United States. From the strain found in Norway and the Ukraine that is said to totally destroy the lungs, to a Tamiflu-resistant strain found in various locations, including a cluster in North Carolina, it is clear that the H1N1 virus is changing. The vaccines created to prevent an influenza infection are only effective for the particular strain of virus used in their creation. Does this mean that the swine flu vaccine will not be effective against the H1N1 mutations?

Tamiflu-resistance

The H1N1 virus has begun to develop a resistance to Tamiflu, also known as oseltamivir phosphate, a commonly used antiviral drug. The swine flu is still sensitive to another antiviral medication, and responds to treatment with Relenza, the prescription form of zanamivir.

D225G receptor binding change

The D225G H1N1 mutation affects the way the H1N1 virus attaches to host cells. This pattern is similar to the 1918 Spanish flu outbreak, which killed as many as 40 million people. Both types of influenza were highly contagious, fast-acting, and attack the deep tissues of the lungs. This causes a total destruction of the lungs, according to Dr. Victor Bachinsky, the head of the Chernivtsi regional forensic bureau.

Testing of MedImmune intranasal vaccine

Flu vaccines currently produced for use in the United States are made by injecting a flu virus into chicken eggs, where the virus replicates for use in the vaccine. During production, it was discovered that the swine flu virus that was reverse engineered for the vaccine did not replicate well in the eggs. In order to improve replication, and increase the amount of vaccine to be produced, genetic material from different viruses was mixed. During the testing process, changes in the receptor binding that resulted from the genetic manipulation did not affect the effectiveness of the vaccine.

Effects of H1N1 mutation on vaccine effectiveness

In an interview with Dr. Henry Niman, President and Founder of Recombinomics, Inc., a company devoted to research in the area of virus evolution, I asked about the potential for H1N1 mutations reducing the effectiveness of the swine flu vaccine. Dr. Niman explained that the D225G mutation was less likely to interfere with vaccine effectiveness. He had this to add:

"Theoretically, one change could significantly impact the vaccine. New isolates are routinely tested with reference antisera for "low reactors". So far one such low reactor was identified in the US, but the virus is beginning to change more rapidly, so more could appear over a short time frame."

*Antisera is the singular form of antiserum. A reference antisera is a sample of blood containing antibodies. Testing is done to see if the antibodies present in the blood react to the new virus.

Someone is finally questioning in the media, what we have already been questioning. With the change in the virus - it makes the current vaccine worthless!

Posted by Sherrie Questioning All at 9:08 AM 1 comments Links to this post



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